The stuff of legend in pop culture. David Vetter was a real boy who, due to a rare immune system disorder, was forced to live his entire life in a germ-free plastic enclosure. Although not originally intended by his doctors as a permanent home, the experimental bubble became the only option for David as bone marrow transplants, a risky procedure in the early 1970s, did not restore his immune system. The film reexamines a fascinating and heartbreaking story of a gamble to preserve life at all costs—a gamble with far-reaching implications that helped to fuel the rise of bioethics.  JH